Two sample MR report
SMDT1_Dendritic Cell (DC) against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 8 | -0.2821456 | 0.2667143 | 0.3308394 |
| Weighted median | 8 | -0.0592190 | 0.0293417 | 0.0435650 |
| Inverse variance weighted | 8 | -0.0526477 | 0.0245471 | 0.0319716 |
| Simple mode | 8 | -0.0719972 | 0.0448796 | 0.1526979 |
| Weighted mode | 8 | -0.0528990 | 0.0425117 | 0.2534207 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.667121 | 6 | 0.9476312 |
| Inverse variance weighted | 2.413844 | 7 | 0.9334438 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.1081162 | 0.1251155 | 0.4207141 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.000353 | 0 | TRUE | 0.0737525 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
